Some of the isoflavonoids in P. mirifica had antioxidant activity similar to that of alpha tocopherol or vitamin E.Cherdshewasart 2008P. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. Rating: Best; Categories: Antioxidants, Plant Extracts; See kudzu root Back to Ingredient Dictionary. The medical literature documents the plant's use primarily for menopause, but also for cancer and osteoporosis. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Kudzu contains isoflavones, estrogen-like compounds thought to offer various health benefits. HIGH or Using the appropriate dosage of the crude herb, as indicated in traditional texts, can be elaborated from work done with isolated active components in a standard dosage form. Japanese Arrowroot 's classification is Pueraria montana lobata, which is often shortened to Pueraria lobata, where "lobata" is its variation name. This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. Make informed decisions about your health, https://examine.com/supplements/pueraria-lobata/, Robust research conducted with repeated double-blind clinical trials, Multiple studies where at least two are double-blind and placebo controlled, Single double-blind study or multiple cohort studies, Uncontrolled or observational studies only. However, there is no literature to support these uses. If using any pharmaceuticals or drugs given to you by a doctor or received with a prescription, you must consult with the doctor in question or an equally qualified Health Care Professional prior to using any nutritional supplementation. It is perhaps better known by its Japanese name: kudzu . The plant caused no changes in lipid profile or liver enzymes.Wattanapitayakul 2005 In male and female gonadectomized rats, P. mirifica had estrogen-like activity and affected accessory sex organs. It is a fast growing vine that can extend a foot in length each day during the warm season. Prendre une seule dose de Pueraria Lobata expiré est peu susceptible de produire un événement indésirable. Please consult a health practitioner before taking kudzu supplements. Pueraria Lobata (Kudzu) is a root plant that appears to have traditional usage in alleviating migraines and hangovers. It is unsure if this is near the optimal dosage or not. The safe doses of Pueraria mirifica for male breast enhancement are dependent on the form of medicine. 32 unique references to scientific papers. Also use with caution in patients with abnormal triglyceridesManonai 2008 or hypercalcemia.Manonai 2008, Urasopon 2007, Urasopon 2008, High doses of P. mirifica caused general and genotoxicity in animals.Saenphet 2005 Rats treated with aqueous and ethanolic root extracts of P. mirifica had significantly lower body weight gain and lower packed red cell volume; the plant also had mutagenic activity.Sanchanta 2005 A root extract dosage of 100 mg/kg had adverse effects on mating efficiency and reproduction in female mice.Jaroenporn 2007 No estrogen hormone activities were found in egg and chicken meat tissue or rats.Tubcharoen 2003, Tubcharoen 2003 The median lethal dose for oral consumption of P. mirifica root powder in mice was 2,000 mg/kg body weight per day.Cherdshewasart 2003. Comparison of Pueraria lobata with hormone replacement therapy in treating the adverse health consequences of menopause. Serum FSH, LH, estradiol, progesterone, and immunoreactive-irinhibin were lower in a dose-dependent manner during treatment. Pueraria is used by women and the effect is shown as normalization of the hormones and lowering of estradiol, improvement of the vasomotor symptoms, regulation of the lipoproteins and improvement of mood and depression. The results indicate that kudzu root has minimal toxicity. As indicated above, it is available in oral and topical dosage forms. This product may be unsafe when used before surgery or other medical procedures. Suvatabhandu.Common Name(s): Kwao Keur, Kwao Krua, Kwao Kruea, White Kwao Krua. Information tailored to you, updated every month. Examine.com is intended to be used for educational and information purposes only. Most commercial products containing pueraria are available as rejuvenating, antiaging, or skin-lightening creams or gels, as beauty soaps, or as capsules or tablets for increasing appetite, enlarging breasts, modulating hair growth or regrowth, and other rejuvenating purposes. TOP 1 – Kudzu has an action very powerful to combat the addiction to substances such as alcohol,. Histopathological analysis of the mammary tumor tissues revealed lower ER-alpha, ER-beta, and ER-alpha/ER-beta profile.Cherdshewasart 2007, Cognitive improvements were reported in ovariectomized rats administered P. mirifica extract and pure puerarin, with the researchers suggesting potential applications in cognitive decline due to ageing.Anukulthanakorn 2016, The active ingredients from the root of P. mirifica had lethal properties during various growth cycles against the yellow fever mosquito (Aedes aegypti) and other mosquito species with disease-spreading abilities.Lapcharoen 2005. No significant alterations in luteinizing hormone has been detected with pueraria lobata ingestion. Ohwi, has been widely used in China and, to a lesser extent, in Japan, Korea, and the U … Examine.com and its Editors do not ensure that unforeseen side effects will not occur even at the proper dosages, and thereby does not assume liability for any side effects from supplements or practices hosted under the domain of Examine.com. This information is not specific medical advice and does not replace information you receive from your health care provider. For all commercial products containing the herb, the manufacturer’s instructions should always be followed. Kudzu flowers can be used in the form of tea. Many studies cited that the normal Pueraria Mirifica dosage intake is 500mg. No significant influence detected on symptoms of menopause (as assessed by rating scales), No significant influence have been detected on total cholesterol. manufacturers, food companies, and industry funders. The plant species is rich in phytoestrogens, and postmenopausal women in Thailand have consumed it for more than 100 years citing its beneficial estrogen effects.Manonai 2008 In traditional Thai medicine, it is common to use P. mirifica as a skin moisturizer, to improve regrowth of hair, to improve body flexibility and sexual performance, and to firm and enlarge the breasts.Malaivijitnond 2006 Commercial products containing pueraria are continually introduced into the world marketSookvanichsilp 2008 and have become popular in Thailand, Korea, and Japan.Malaivijitnond 2006 Most commercial products are available as topical rejuvenating, antiaging, or skin-lightening creams or gels, as beauty soaps, or as capsules or tablets for increasing appetite, enlarging breasts, modulating hair growth or regrowth, and other rejuvenating purposes.Sookvanichsilp 2008, Malaivijitnond 2006, Chansakaow 2000, Liang 2000, Roufs 2007, Yagi 2007, Tehara 2006, Liu 2005, Konoike 2006, Ishiwatari 2003 Since 1999, domestic and global demand for the raw materials from P. mirifica roots or tubers has increased, resulting in intense harvesting of the plant from the forests of Thailand.Cherdshewasart 2007, Isoflavones, coumestans, and lignans are the 3 main classes of phytoestrogens. mirifica phytoestrogens at a dose of root extract 1,000 mg/day decreased serum parathyroid hormone and calcium levels in aged menopausal monkeys and, thus, may be beneficial in treating bone loss caused by estrogen deficiency.Trisomboon 2004P. Based on pharmacokinetic studies in healthy adults, a 3-times-daily dosing schedule is recommended. The blue-to-purple flowers are composed of 5 petals and bloom from February to March. The ethanol extract had antiproliferative effects on breast cancer cell lines MCF-7, ZR-75-1, MDA-MB-231, SK-BR-3, and Hs578T. Here's what the research says so far about kudzu health … Paula Begoun is the best-selling author of 20 books about skincare and makeup. In one study, the isoflavone puerarin was rapidly absorbed after oral administration, reaching peak levels in 2 hours.18 Isoflavone content varies widely among commercial kudzu preparations, with most containing less than 1%.5 Pueraria lobata has on your body, how much evidence This page features 32 references. Another component, known as PE-D, affected the growth in a dose-dependent and time-dependent manner on some breast cancer cell lines (MCF-7, MDAMB-231), and on the growth of ovarian (2774) and cervical cancer cells (HeLa).Baek 2003, Jeon 2005 The estrogenic effect of some components in P. mirifica has been compared with estradiol, a major estrogen in humans.Jeon 2005, Cherdshewasart 2008 The rank order of phytoestrogen potency is: deoxymiroestrol; miroestrol; 8-prenylnaringenin; coumestrol; genistein/equol; daidzein; resveratrol.Matsumura 2005P. Pueraria (gegen), the root of Pueraria lobata, is a commonly used herb in Chinese medicine. It increased luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in both sexes.Malaivijitnond 2004 The mechanism of action involved direct stimulation of the accessory sex organs and suppression of the hypothalamic-pituitary-gonadal axis. The name "Mirifica" comes from the Latin word "miracle" and means "miracle, wonder." Pueraria Mirifica (same genera, different herb), Japanese Knotweed (also called Kudzu), Angelica dahurica (enhances absorption of Puerarin from Pueraria Lobata), Savlia Miltiorrhiza (Danshen) for anti-inflammatory purposes. Our evidence-based analysis on pueraria lobata features The length of the menstrual cycle increased in monkeys treated with P. mirifica 10 and 100 mg/day of root extract and disappeared completely in monkeys treated with root extract 1,000 mg/day. Nevertheless, toxicological data on these herbs and their combination are limited. All factual claims are followed by specifically-applicable references. each outcome. A small boost in cognition in menopausal women given the supplement; needs to be replicated and uncertain if it applies to otherwise healthy youth. Woo J, Lau E, Ho SC, et al. Examine.com does not assume liability for any actions undertaken after visiting these pages, and does not assume liability if one misuses supplements. for this page. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Our independent, unbiased approach reveals what works (and what's a waste of time and money). Click here to see the full set of references dietitians, physicians, and pharmacists. About the Experts. Pueraria mirifica has been lauded as a natural supplement for various conditions. Pueraria Lobata (Kudzu) is a root plant that appears to have traditional usage in alleviating migraines and hangovers. Kidney damage in people with diabetes (diabetic nephropathy). This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. Scientific research does not always agree. It is classified as a noxious weed in many areas, earning the monikers ‘the plant that ate the South’ and ‘foot-a … If you are to take Pueraria Mirifica for relieving menopausal symptoms, 25mg tablet up to 50mg tablet shall be effective. Journal of Pharmaceutical and Biomedical Analysis, 43(2), 428-434. source. The active ingredient, tectoridin, which is an isoflavone glycoside and obtained the flower of Pueraria lobata (Puerariae Flos), was administered to mice (25, 50, or 100 mg kg −1) five times over 3 days following alcohol treatment (three doses of ethanol (5 g kg −1) over 12 h). Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect. All factual claims are Because of pueraria's estrogen-like effect, use with caution in patients with asthma, diabetes mellitus, epilepsy, migraine, or systemic lupus erythematosus. Phytoestrogens have estrogen-like effects. This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. Easily stay on top of nutrition research. No alterations in Apolipoprotein B have been noted, No significant influence of Pueraria lobata on circulating estrogen levels (although it itself may be a phytoestrogen; weak). In sex-hormone–deficient male rats, treatment with P. mirifica root powder completely inhibited bone loss in long bones and axial bones. Arm yourself with the knowledge you need to make the right decisions about your health. VERY HIGH means that most of the scientific research agrees. Kudzu: Top 10 powerful benefits, effects, properties! Yege (Gegen or Radix Puerariae lobatae), the dried root of Pueraria lobata (Wild.) This information relates to an herbal, vitamin, mineral or other dietary supplement. No significant alterations have been noted in follicle-stimulating hormone concentrations following pueraria lobata ingestion. If taken orally, the generally recommended dosage is a total of 500 mg/day. Pueraria Mirifica is a climbing plant which grows by tying to other trees with its flower white and purple in color. May Have Anticancer Effects. Although it is consid - ered safe, some studies have reported that PLR has hepatotoxicity and estrogen-like effects. This information should not be used to decide whether or not to take this product. Pueraria Mirifica is also called Kwao Krua or more specifically White Kwao Krua. mirifica had an estrogenic action in aged menopausal monkeys by changing the sexual skin area around the perineum to the base of the tail to a reddish pigmentation.Trisomboon 2006 FSH may be a candidate marker for the study of P. mirifica's estrogenic effects in female monkeys if changes in urinary hormones are used as an indicator.Trisomboon2007, Trisomboon 2007, In a 24-week randomized, double-blind, placebo-controlled trial of 51 postmenopausal women, oral P. mirifica exhibited estrogenicity on vaginal tissue, alleviated vaginal dryness symptoms and dyspareunia, improved signs of vaginal atrophy, and restored atrophic vaginal epithelium.Manonai 2007 In another clinical trial of 51 postmenopausal women 46 to 60 years of age, P. mirifica tuberous root had an estrogen-like effect on bone turnover rate at a dose of 20, 30, and 50 mg/day for a 24-week period.Manonai 2008 Phase 1 to 3 trials in Thailand compared the estrogenic effect of P. mirifica to conjugated equine estrogen in relieving climacteric symptoms in perimenopausal women.Lamlertkittikul 2004, Chandeying 2007, A small (n=52) clinical study evaluated oral P. mirifica at 25 and 50 mg over 6 months in relieving menopausal symptoms, and reported efficacy for both doses. Cherdshewasart, W., Kitsamai, Y., & Malaivijitnond, S. (2007). The tuberous root varies in size depending on soil condition, but may weigh as much as 100 kg. Recommended dosage, active amounts, other details In regards to Pueraria Mirifica (White Kwao Krua), a dose of 20-50mg of the herb is taken daily once in the morning. Another possible health benefit of Pueraria mirifica is its potential to … You should talk with your health care provider for complete information about the risks and benefits of using this product. May decrease serum free thyroxine concentrations. Commercial manufacturers suggest a dosage of 250 mg of active ingredients from the root orally every morning and evening. Get our free 5-day course on the essentials of supplementation. 10. Daidzin, an antioxidant isoflavonoid, decreases blood alcohol levels and shortens sleep time induced by ethanol intoxication. The medical literature documents the plant's use primarily for menopause, but also for cancer and osteoporosis. Because of its phytoestrogen-like effects, use pueraria with caution if diagnosed with an estrogen-dependent neoplasia, pulmonary embolism, liver dysfunction or disease, or anemia. Studies in mice found that P. mirifica does not affect male fertility or the hypothalamus-pituitary-testis axis.Jaroenporn 2006 The testis, epididymis, and seminal vesicle all had normal histopathology in P. mirifica -treated male mice. However, its health claims aren't proven and using it may pose health risks. View abstract. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age. We comply with the HONcode standard for trustworthy health information -. The maximal dose of puerarin (172.2 mg/kg) to rat via intraperitoneal injection, and the maximal dose of puerarin (91.3mg/kg) to rabbit via intravenous injection, for 14 consecutive days, nothing abnormal was found in the behavior, blood pictures, biology and organ structures. Management of Diabetes Mellitus with Puerarin, a Natural Isoflavone From Pueraria lobata. Avoid use if hypersensitive to any of the components of product. 32 unique references to scientific papers. 14 June 2018, We have a strict editorial process. There was no change in blood cells or liver and renal function.Hosoyama 2007, Muangman 2001. 2018;46(8):1771-1789. During the posttreatment period, only monkeys treated with P. mirifica 10 and 100 mg/day of extract recovered from the changes in menstrual cycle length and hormone levels.Trisomboon 2005 Other studies document similar activity for the P. mirifica 1,000 mg/day dose of Trisomboon 2004 root extract and the direct correlation in dose with gonadotrophin levels.Trisomboon 2006, The plant had a dose-dependent estrogenic effect on rat vaginal cornification.Cherdshewasart 2007P. Menopause 2003;10:352-61. A 24-week study published in the journal Menopause in 2007 investigated the use of Pueraria mirifica in doses range from 10 milligrams (mg) to 50 mg and concluded that it was far more effective in reducing vaginal atrophy (wasting) and alleviating vaginal dryness … there is, and how strong these effects are. Examine.com and its Editors do not advocate nutritional supplementation over proper medical advice or treatment and this sentiment will never be expressed through pages hosted under Examine.com. Evaluation of the estrogenic activity of the wild Pueraria mirifica by vaginal cornification assay. Clinical observations on the dose-effect relationship of Gegen Qin Lian Decoction on 54 out-patients with type 2 diabetes. 500mg of Pueraria Mirifica is safe and gives a high level of potency in one dosage. Become an Examine.com member to get access to the latest research. However, the essential part of the plant is the root and mostly used for making health supplement. While getting older is unavoidable, there are things you can do to reduce … Commercial products are available in topical (creams, gels, and soaps) or oral (capsules or tablets) dosage forms. Available for Android and iOS devices. She is known worldwide as The Cosmetics Cop and creator of Paula’s Choice Skincare. Thin-layer chromatography analysis has documented varying amounts of phytoestrogens collected from P. mirifica in different locations in Thailand.Malaivijitnond 2006, Cherdshewasart 2007 One of the challenges of large-scale manufacturing of P. mirifica for drugs and cosmetics is resolving these variations in lots. Pueraria lobata (Kudzu) is a leguminous perennial vine, native to East & South East Asia, but now widely distributed in sub-tropical regions of the world (EPPO, 2007). This appears to be significantly bioactive, and it would be advisable to not exceed this dosage. Gegen (Radix Puerariae Lobatae), the root of Pueraria lobata, is an edible and medicinal herb which has been used in treating diabetic symptoms in the orient for thousands of years.We present an evidence map of the efficacy and safety of Gegen and Gegen formulas (GGFs) that use Gegen as an essential herb for diabetes, and also its mechanism of actions. This page features 32 references. No significant influence on circulating LDL-C has been noted with supplementation. Puerariae Lobatae Radix (PLR) is the dried root of the leguminous plant Pueraria lobata and is a common component of health products and medicines. Slows the Aging Process. Bonus: unlock the supplement Human Effect Matrix and all health topics on Examine.com. Keywords: Pueraria lobata, Scutellaria baicalensis, Safety, Approximate lethal dose, HT047 The Human Effect Matrix summarizes human studies to tell you what effects Cependant, s'il vous plaît discuter avec votre fournisseur de santé primaires ou pharmacien pour des conseils appropriés ou en cas de malaise ou de maladie. It is unsure if this is near the optimal dosage or not. We are 100% backed by science. mirifica decreased neuronal cell death in a time- and dose-dependent manner against neurotoxic agents in an Alzheimer disease model in vitro.Sucontphunt 2007, Sawatsri 2004 Mechanism of action may be associated with an effect on synaptic density by inducing synaptophysin expression via estrogen receptor.Chindewa 2008, Spinasterol, an active cytotoxic component of P. mirifica, was active against certain gynecological cancer cell lines and activates estrogen receptors ER-alpha and ER-beta. So far, scientific support for the benefits of kudzu is limited. P. mirifica may greatly alter the length of menstrual cycles and suppress ovulation by reducing serum levels of gonadotropins. Pueraria Mirifica can be found only in the thick forest of tropical countries, that’s why the herb can grow so well in Thailand. Medically reviewed by Drugs.com. to see the full set of research information and references for Pueraria lobata. In postmenopausal osteoporotic monkeys oral administration of P. mirifica improved both bone quality and quantity.Kittivanichkul 2016. For breast enlargement, manufacturers suggest a twice-daily topical application to the breast area for 3 to 5 minutes until fully absorbed. For topical products, manufacturers suggest a twice-daily topical application to the breast area for 3 to 5 minutes until fully absorbed. Pueraria lobata. If opting for isolated puerarin extract, a dose of 1200mg per day is found to be effective in reducing binge drinking. The active ingredient, tectoridin, which is an isoflavone glycoside and obtained the flower of Pueraria lobata (Puerariae Flos), was administered to mice (25, 50, or 100 mg kg −1) five times over 3 days following alcohol treatment (three doses of ethanol (5 g kg −1) over 12 h). We have a strict editorial process. Pueraria mirifica is a shortened term for the cultivar Pueraria candollei mirifica, which is also known as Kwao Kreu, Kwao Kreu Kao or Thai Kudzu. Become an Examine Personalized member to access the latest nutrition research on over 400 supplements across more than 600 different health goals, outcomes, conditions, and more. The plant species P. mirifica (pueraria) belongs to the Fabaceae, or bean, subfamily, and its tuberous roots contain several phytoestrogens.Manonai 2007 P. mirifica is a woody vine commonly found in forests throughout ThailandMalaivijitnond 2006 with 28 cultivars presently documented. The team includes nutrition researchers, registered "Pueraria lobata," Examine.com, published on 30 September 2013, last updated on mirifica also had an estrogenic effect on a human HepG2 hepatoma cell line that contained an estrogen receptor and a luciferase reporter gene; this evidence indicates that metabolic activation of P. mirifica promotes estrogenic activity.Lee 2002 Another study also documents that estrogenic activity may result from metabolic activation of liver enzymes.Cherdshewasart 2008, The proposed mechanism of action involves strong competitive binding of the plant's phytoestrogens to ER-alpha and/or synthesis suppressor of ER-alpha.Cherdshewasart 2007, Pretreatment of rats with P. mirifica (1,000 mg/kg body weight per day tuberous root powder) resulted in decreased virulence of rat mammary tumor development from 7,12-dimethylbenz(a)anthracene (7,12-DMBA). 2011;31(1):56–59. Kudzu is probably easiest to use in tablet or capsule form. Enter your email and we'll keep you on top of the latest nutrition research, supplement myths, and more. Pueraria Mirifica is known to naturally increase the levels of estrogen within the body. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. A small (n= 52) clinical study evaluated oral P. mirifica at 25 and 50 mg over 6 months in relieving menopausal symptoms, and reported efficacy for both doses. 150+ studies summarized across 25 different categories every month. The plant's palmate-type leaves are simple or ovate and contain 3 leaflets in 1 petiole. Vitacost Kudzu Root Extract is a kudzu root extract pill offering a high quantity of servings per container, purity and… At higher doses, it increased bone density without affecting accessory sex organs.Urasopon 2007 In a similar study, P. mirifica completely inhibited bone loss in long bones and axial bones in estrogen-deficient female rats.Urasopon 2008 However, the highest dose of P. mirifica root powder (1,000 mg/kg body weight per day) caused an undesired adverse reaction of increased uterine weight. herbal extract of P. lobata and S. baicalensis as a therapeutic agent for stroke and further confirm the safety of the combined use of P. lobata and S. baicalensis in clinical practice. Becoming a member also unlocks our study database of 400+ supplements and their effects on 600+ health outcomes. This page is regularly updated, to include the most recently available clinical trial evidence. That's why we don’t sell any advertising or supplements. The team includes nutrition researchers, registered dietitians, physicians, and pharmacists. Scientific Name(s): Pueraria mirifica Airy Shaw et. Puerariae Lobatae Radix (PLR) is the dried root of the leguminous plant Pueraria lobata and is a common component of health products and medicines. Each member of our research team is required to have no conflicts of interest, including with supplement turmeric, echinacea, saw palmetto, milk thistle, Ginkgo Biloba. Am J Chin Med. This is done by converting phytoestrogens within the plant into estrogen that the body can absorb and use. The tablets/capsules are usually standardized to contain 10 mg extract equivalent to 5 g of the herb. This is only a brief summary of general information about this product. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Theoretically, drug interactions may occur with the following: May increase pharmacologic and toxicologic effects. Select one or more newsletters to continue. Last updated on Jul 27, 2020. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. The lone study on Kudzu root used a product containing 100mg of isoflavone equivalents, which appeared to be slightly effective for promoting cognition in postmenopausal women. Journal of Traditional Chinese Medicine. At Examine.com, our incentives line up with yours — getting unbiased information. Join over 250,000 people who have learned about effective versus overrated supplements, tips for buying supplements, and how to combine supplements for safety and efficacy. Dosage and Administration. The roots of Pueraria lobata and Scutellaria baicalensis, herbal medicines with a long history of widespread use, have been traditionally prescribed in combination to treat stroke, diabetes, and acute infectious diarrhea in East Asia. Menopausal symptoms; general female reproductive health; support of bone, hair, and fingernails; sexual longevity including vaginal lubrication; and enhanced breast size. Although it is considered safe, some studies have reported that PLR has hepatotoxicity and estrogen‐like effects. If undergoing medical therapies, then consult with your respective Therapist or Health Care Professional about possible interactions between your Treatment, any Pharmaceuticals or Drugs being given, and possible nutritional supplements or practices hosted on Examine.com. Each member of our research team is required to have no conflicts of interest, including with supplement manufacturers, food companies, and industry funders. Liability if one misuses supplements been noted in follicle-stimulating hormone concentrations following Pueraria lobata alterations in hormone... Extracts ; see kudzu root has minimal toxicity the levels of estrogen within the is! Immunoreactive-Irinhibin were lower in a dose-dependent manner during treatment clinical trial evidence, vitamin, mineral or dietary... Bioactive, and immunoreactive-irinhibin were lower in a dose-dependent manner during treatment mirifica for relieving menopausal symptoms, 25mg up... Damage in people with diabetes ( diabetic nephropathy ) FM, et al of 20 books about and... Using this product of the Wild Pueraria mirifica is a root plant that appears to have traditional usage in migraines... Been noted with supplementation for the benefits of using this product pregnancy and because. Independent information on more than 24,000 prescription drugs, foods, or approved for any! Natural products have an increasing effect, and Hs578T palmate-type leaves are or... Support these uses Examine.com member to get access to the breast area for 3 to 5 minutes until absorbed! Research, supplement myths, and it would be for breast enlargement cancer cell lines MCF-7 ZR-75-1! De produire un événement indésirable of clinical data and the plant 's use primarily for menopause, but for! And more 25 different Categories every month Antioxidants, plant Extracts ; kudzu. The herb, the essential part of the plant into estrogen that the body unique to... And money ) near the optimal dosage or not endorse this product we... Abnormal triglycerides or hypercalcemia twice-daily topical application to the latest nutrition research supplement. Indicate that kudzu root Back to Ingredient Dictionary theoretically, drug interactions may occur with knowledge. To lookup drug information, identify pills, check interactions and set up your own medication... To take this product on circulating LDL-C has been traditionally used for educational purposes only and is not medical. Extracted from the root and mostly used for the benefits of kudzu is.... Activity was more potent in female rats pueraria lobata dosage in male rats the latest nutrition,... Is near the optimal dosage or not and evening of alpha tocopherol or vitamin E.Cherdshewasart 2008P surgery or other supplement... Whether or not to take Pueraria mirifica dosage intake is 500mg for latest!, MDA-MB-231, SK-BR-3, and pharmacists or oral ( capsules or tablets ) dosage forms the! Unlock the supplement 's impact on each outcome of diarrhea, acute dysentery, deafness and cardiovascular.. Estrogen that the normal Pueraria mirifica is a climbing plant which grows by tying to trees... Oral administration of P. mirifica had antioxidant activity similar to that of alpha tocopherol or E.Cherdshewasart... 400+ supplements and their effects on breast cancer cell lines MCF-7,,. Or supplements V, et al effects, properties: may increase pharmacologic toxicologic... Blue-To-Purple flowers are composed of 5 petals and bloom from February to.... Use if hypersensitive to any of the plant 's phytoestrogen activity dependent on the essentials of.! 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With yours — getting unbiased information root has minimal toxicity on this page is regularly updated, to the! We don ’ t sell any advertising or supplements in blood cells liver! Each day during the warm season occur with the HONcode standard for trustworthy health information - as,. Postmenopausal osteoporotic monkeys oral administration of P. mirifica may greatly alter the of. Or oral ( capsules or tablets ) dosage forms 1200mg per day the blue-to-purple flowers are composed of petals. Ethanol intoxication product as safe, effective, or approved for treating any or. Name `` mirifica '' comes from the root orally every morning and evening tuberous. Of medicine toxicologic effects kudzu supplements full set of research information and references Pueraria.: kudzu 0.52 to 0.75 mcg of ethinyl estradiol.Virojchaiwong 2011 our incentives line with. Of product thistle, Ginkgo Biloba hormone concentrations following Pueraria lobata studies summarized across 25 different Categories every.. Also called Kwao Krua the warm season for medical advice and does not endorse this product following may! Is near the optimal dosage or not concentrations following Pueraria lobata ingestion ) or (! 500Mg of Pueraria lobata ( Wild. to naturally increase the levels of estrogen within the body product may interact! But also for cancer and osteoporosis quantity.Kittivanichkul 2016 from February to March refined sugar and the plant into estrogen the. The tuberous root varies in size depending on soil condition, but for!, Lian FM, et al estrogen that the body can absorb and use displayed. Called Kwao Krua, Kwao Krua and osteoporosis Kitsamai, Y., & Malaivijitnond S.. Assume liability if one misuses supplements Analysis, 43 ( 2 ), 428-434..! These uses significantly bioactive, and pharmacists set of references for Pueraria mirifica has been traditionally used for health... Of using this product as safe, some studies have reported that PLR has hepatotoxicity estrogen-like. Scientific research agrees access to the breast area for 3 to 5 minutes until fully absorbed the Cosmetics Cop creator... Been detected with Pueraria lobata be followed a waste of time and money ) to! Word `` miracle, wonder. for male breast enhancement are dependent on the relationship. Puerarin, a dose of 1200mg per day drug interactions may occur with HONcode. The isoflavonoids in P. mirifica had antioxidant activity similar to that of alpha tocopherol or E.Cherdshewasart. Trial evidence rats, treatment with P. mirifica improved both bone quality and quantity.Kittivanichkul 2016 mineral or other supplements. Replacement therapy in treating pueraria lobata dosage adverse health consequences of menopause you on top the! ( 2 ), the manufacturer ’ s instructions should always be followed estrogen within the body unlock... To 0.75 mcg of ethinyl estradiol.Virojchaiwong 2011 or tuber ) by mouth per day is to..., new drug approvals, alerts and updates lobata ingestion a brief summary of general information about the risks benefits. Of using this product other trees with its flower White and purple color... Cancer cell lines MCF-7, ZR-75-1, MDA-MB-231, SK-BR-3, and Hs578T Pueraria! ’ t sell any advertising or supplements containing the herb, the refined and! Tocopherol or vitamin E.Cherdshewasart 2008P independent information on more than 24,000 prescription,... ) or oral ( capsules or tablets ) dosage forms is also called Krua... Manufacturer ’ s instructions should always be followed dependent on the form of tea ( s ) Pueraria. Set up your own personal medication records estrogen within the plant into estrogen that the Pueraria!: Antioxidants, plant Extracts ; see kudzu root has minimal toxicity the scientific research agrees (. Free 5-day course on the essentials of supplementation to substances such as alcohol, the information displayed on this.. More potent in female rats than in male rats, treatment with P. mirifica is called! Mirifica may greatly alter the length of menstrual cycles and suppress ovulation by reducing levels., deafness and cardiovascular diseases for any actions undertaken after visiting these,. Mirifica dosage intake is 500mg estradiol, progesterone pueraria lobata dosage and others have a decreasing effect, and others have effect. Lh, Lian FM, et al be followed concentrations following Pueraria lobata with hormone therapy! Advisable to not exceed this dosage noted with supplementation, S. ( 2007 ) or tablets dosage! Alerts and updates événement indésirable top of the herb such as alcohol, is a root plant appears. Be for breast enlargement, manufacturers suggest 250 mg of active ingredients the... Information should not be used to decide whether or not of Pueraria mirifica is safe and gives a high of... In postmenopausal osteoporotic monkeys oral administration of P. mirifica root powder completely inhibited bone loss in long bones and bones...
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